The CIRBP antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CIRBP, and CIRP. This antibody recognizes Human, Mouse, and Rat antigen. The CIRBP antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed